Gb88-001

gb88B ) PAR2 antagonist GB88 (1.6 Ϯ 0.5 ␮ M) was 1000-fold more potent than ENMD-1068 (1.2 Ϯ 0.4 mM) in preventing trypsin-induced intracellular calcium release ([Ca 2 ϩ ] i ) in HMDMs ( n ϭSuen JY, et al. Modulating human proteinase activated receptor 2 with a novel antagonist (GB88) and agonist (GB110). Br J Pharmacol. 2012 Mar;165(5):1413-23. [Content Brief]